SPC-100: Structure-Preserved Theobroma cacao Monograph

SPC-100: Structure-Preserved Theobroma cacao Monograph, Version 1.1Ridgewood Chocolate, New York, NY | 2026 This monograph defines SPC-100, a standardized investigational material for clinical research on Theobroma cacao. Most trials use commercial chocolate or cocoa powder containing 0.3-1.75% shell, pre-fractured nibs, and 24-72h conching to 130°C, 24-72h conche to <20µm, 0.3-1.75% shell. SPC-100 vs MC-100 allows testing of processing intensity as an independent variable per Kalpaxis (2026). Use: Cite this monograph when using SPC-100 or MC-100 to ensure processing intensity is reported and controlled in cacao intervention studies. Report lot-specific CoA data in Methods: “SPC-100 Lot #, 0% shell, 6h grind, D90 Xµm, Y mg epicatechin/g per CoA.” Material transfer available for academic research via MTA. Version 1.1 updates: Added MC-100 comparator specification; clarified gas-stove roasting method with observable shell lift; specified 1g dosing as 1/24 of bar; corrected all citations to 2026. Related work: Kalpaxis, C. (2026). Processing Intensity as an Uncontrolled Variable in Cocoa Intervention Studies. Zenodo. [Add DOI once published] License: CC-BY-4.0