Development, Evaluation and In Silico Study of QR-Enabled CogniGut Chocolate for Gut-Brain Axis Support and Digestive Wellness

This study is about the making of a new chocolate based delivery system, which comes with digestive herbs and adaptogenic compounds. The idea is to boost gastrointestinal wellness and also improve the patient’s willingness to take it regularly. Usual dosage formats like syrups and powders can be kind a tricky, because they often show weak palatability and lower acceptance. So to handle those limits, an adaptogenic digestive chocolate was prepared using a cocoa base together with plant ingredients such as Ginger, Ajwain, Cumin, Tulsi, Brahmi, and Mint. After preparation, the formulation was checked for sensory features and physicochemical properties. What came out showed decent appearance , taste, texture , and overall stability. The melting point stayed around 33–35°C , and the pH was 6 ± 0.1 . Then in-silico work was carried out, and the molecular docking results suggested moderate to strong binding between thymol, menthol, and bacoside with digestive as well as neurological targets. ADME findings also pointed toward good absorption and bioavailability for thymol, menthol, and eugenol, whereas the toxicity prediction suggested very low safety worries.Overall, the work concludes that the developed product is a promising nutraceutical, it feels patient-friendly, and it is kind of innovative in nature. It also may offer digestive plus adaptogenic support. The final formulation was named “CogniGut Chocolate”, meaning it aims at both digestive comfort and gut-brain axis support, using a mix of digestive herbs and adaptogenic botanicals.